Most antipsychotic medications aren’t approved for the treatment of anxiety disorders, such as panic disorder and generalized anxiety disorder. Because antipsychotics can have adverse effects, we encourage prescribing providers to carefully assess symptoms, risks and benefits in prescribing medications for our members with anxiety disorders.
Our Behavioral Health Clinical Practice Guidelines have evidence-based information from nationally recognized sources. These are intended to provide a framework for patient care but not substitute for clinical judgment in individual cases. Following are guidelines related to anxiety disorder:
- Practice Guideline for the Treatment of Patients with Panic Disorder, Second Edition (2009) American Psychiatric Association
- Diagnosis and Management of Generalized Anxiety Disorder and Panic Disorder in Adults (2015) American Family Physician
- Clinical Practice Guideline for the Assessment and Treatment of Children and Adolescents with Anxiety Disorders (2020) American Academy of Child & Adolescent Psychiatry
- VA/DoD Clinical Practice Guideline for Management of Posttraumatic Stress Disorder and Acute Stress Disorder (2023) Department of Veterans Affairs/Department of Defense
For more information on medications in behavioral health care, see our Quick Reference on Potential Side Effects.
Closing Gaps in Our Members’ Care
People with serious mental illness who use antipsychotic medications are at increased risk of diabetes, according to the National Committee for Quality Assurance. Regular screening for diabetes is important for detecting, monitoring and in the treatment of the disease. We track the NCQA quality measure Diabetes Screening for People With Schizophrenia or Bipolar Disorder Who Are Using Antipsychotic Medications. SSD tracks the number of people 18 to 64 years old with schizophrenia or bipolar disorder who were dispensed an antipsychotic medication and had an annual diabetes screening.